TitleDevelopments in metabolic engineering.
Publication TypeJournal Article
Year of Publication1997
AuthorsCameron, DC, Chaplen, FW
JournalCurr Opin Biotechnol
Volume8
Issue2
Pagination175-80
Date Published1997 Apr 1
ISSN1879-0429
Abstract

The complete sequencing of several microbial genomes has resulted in the increased availability of genes for metabolic engineering. The number of databases and computational tools to deal with this information has also increased. This development has stimulated, and will continue to stimulate, advances in metabolic engineering. Specific recent advances include improvement of pathways for aromatic metabolites, the development of a more complete understanding of the effect of bacterial hemoglobin on cell performance, the development of NMR-based methods for the monitoring of intracellular metabolites and metabolic flux, and the application of metabolic control analysis and metabolic flux analysis to a variety of systems.

Alternate JournalCurr. Opin. Biotechnol.
PubMed ID9079723